Is ferritin normal in thalassemia?
The serum ferritin is decreased in iron deficiency, normal in thalassemia, and increased in chronic infection.
Does thalassemia cause high ferritin levels?
Results: 87.4% of the beta thalassaemia major patients showed very high ferritin levels. The mean serum ferritin level was found to be 2767.52 ng/ml. 44.4% patients had serum ferritin between 1000 to 2500 ng/ml, while 43.05% patients had values above 2500 ng/ml.
Is ferritin high in thalassemia minor?
The serum ferritin levels in both Hb H and beta-thalassemia/Hb E patients were higher than normal. They were higher in beta-thalassemia/Hb E than Hb H disease.
Can ferritin be low in thalassemia?
The results show that the level of serum ferritin in 100 (74%) cases was within normal limits, in 17 (12.6%) cases it was above the normal range, whereas in 18 (13.4%) cases the level was lower than normal. The importance of serum ferritin estimation in carriers of the beta-thalassaemia trait is highlighted.
What should ferritin levels?
The normal range for blood ferritin is: For men, 24 to 336 micrograms per liter. For women, 11 to 307 micrograms per liter.
Should thalassemia patients take iron?
People with thalassaemia may be advised to avoid iron supplements because they are at risk of iron overload. Carriers of the thalassaemia gene may be asymptomatic but pregnancy can precipitate anaemia and there is a chance that this may be inappropriately treated with iron replacement.
What is dangerously high ferritin levels?
Many laboratories consider serum ferritin levels greater than 200 ng/mL in women and greater than 300 ng/mL in men to be abnormal. However, a large percentage of the general population has a serum ferritin level between 200 and 1,000 ng/mL.
How do I lower ferritin levels?
Dietary changes can include:
- avoiding supplements that contain iron.
- avoiding supplements that contain vitamin C, as this vitamin increases iron absorption.
- reducing iron-rich and iron-fortified foods.
- avoiding uncooked fish and shellfish.
- limiting alcohol intake, as this can damage the liver.
Is thalassemia linked to leukemia?
The coexistence of thalassemia with cancers such as Hodgkin disease, lymphoma, seminoma, and leukemia has been reported [3,4,5,6,7]. This coexistence could be explained by either genetic or environmental interactions, or it might be thought of as just a coincidence.
What is the difference between thalassemia minor and thalassemia trait?
People who have thalassemia trait (also called thalassemia minor) carry the genetic trait for thalassemia but do not usually experience any health problems except perhaps a mild anemia. A person may have either alpha thalassemia trait or beta thalassemia trait, depending upon which form of beta protein is lacking.
Does thalassemia cause iron deficiency?
It has long been considered that iron deficiency does not exist in thalassemia syndromes, including thalassemia major as well as trait. However, studies have shown the occurrence of iron deficiency in patients with beta thalassemia trait (BTT).
How do I get my ferritin levels down?
Dietary changes
- avoiding supplements that contain iron.
- avoiding supplements that contain vitamin C, as this vitamin increases iron absorption.
- reducing iron-rich and iron-fortified foods.
- avoiding uncooked fish and shellfish.
- limiting alcohol intake, as this can damage the liver.
What causes high ferritin levels?
A doctor would expect higher than normal ferritin levels in people with these and other inflammatory conditions. The most common causes of elevated ferritin levels are obesity, inflammation, and daily alcohol intake. The most common causes of genetic-related elevated ferritin levels is the condition hemochromatosis.
Are high ferritin levels dangerous?
Ferritin levels in men hover between 30 to 400 nanograms per milliliter. High ferritin levels may cause fatigue. High ferritin levels may cause muscle aches and pains. High ferritin levels may cause heart problems.
What does low ferritin signify?
Ferritin is an indication of the amount of iron in storage in your body. Low ferritin levels are often associated with symptoms such as fatigue, shortness of breath, inability to exercise and even hair loss.
What is normal ferritin?
For women, the normal range of ferritin in your blood is 20 to 500 nanograms per milliliter. For men, the normal range is 20 to 200 nanograms per milliliter. Higher than normal levels may indicate a number of diseases or conditions, including liver disease and hyperthyroidism.
