What drugs are Sialogogues?

10,26 “Xerogenic” medications associated with a low unstimulated saliva flow are: psycholeptics, psychoanaleptics (particularly selective serotonin reuptake inhibitors), oral antidiabetics (mainly sulfonylureas), respiratory agents, quinine, antihypertensive agents (such as thiazides and calcium channel blockers).

Which drugs increase saliva?

Prescribe medication that stimulates saliva. Your doctor may prescribe pilocarpine (Salagen) or cevimeline (Evoxac) to stimulate saliva production.

Is it bad to swallow saliva?

Swallowing saliva further protects the digestive tract by shielding the esophagus from harmful irritants, and helping to prevent gastrointestinal reflux (heartburn).

How can I increase saliva in my mouth naturally?


  1. Chew sugar-free gum or suck on sugar-free hard candies to stimulate the flow of saliva.
  2. Limit your caffeine intake because caffeine can make your mouth drier.
  3. Don’t use mouthwashes that contain alcohol because they can be drying.
  4. Stop all tobacco use if you smoke or chew tobacco.
  5. Sip water regularly.

Why is parotitis so painful?

Infection. Acute parotitis is an extremely painful condition as the parotid gland is invested with a richly innervated fascia.

What are symptoms of parotitis?


  • Face pain.
  • Fever.
  • Headache.
  • Sore throat.
  • Loss of appetite.
  • Swelling of the parotid glands (the largest salivary glands, located between the ear and the jaw)
  • Swelling of the temples or jaw (temporomandibular area)

How can I produce more saliva instantly?

Chewing and sucking help stimulate saliva flow. Try: Ice cubes or sugar-free ice pops. Sugar-free hard candy or sugarless gum that contains xylitol….These products may also help:

  1. Artificial saliva products to help you produce more saliva.
  2. Toothpastes and mouthwashes specially made for dry mouth.
  3. Lip balm.

What medications increase saliva production?

Salagen is commonly prescribed to help with low saliva production. Evoxac is a medication that is used to increase saliva production for those that have Sjögren’s syndrome, which is a disease that causes dry eyes, mouth, and skin.

What medications increase salivary flow?

A sialogogue, sialagogue, ptysmagogue or ptyalagogue is a drug or substance that increases the flow rate of saliva. Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva.

What does medication increase saliva?

Your health care provider may also prescribe Salagen, a drug that increases the natural production of saliva. Another prescription drug, Evoxac, is FDA-approved for the treatment of dry mouth in people with Sjögren’s syndrome, an autoimmune disease associated with dry eyes, dry mouth, dry skin, and muscle pain.

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