What ingredients are in oxaliplatin?
Oxaliplatin is an antineoplastic active substance belonging to a new class of platinum-based compounds in which the platinum atom is complexed with 1,2-diaminocyclohexane (“DACH”) and an oxalate group.
Is oxaliplatin hydrophobic or hydrophilic?
Oxaliplatin is a platinum agent that is used for treatment of colorectal cancer. A sensitive and selective hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the quantification of oxaliplatin was developed.
What is oxaliplatin injection?
OXALIPLATIN (ox AL i PLA tin) is a chemotherapy drug. It targets fast dividing cells, like cancer cells, and causes these cells to die. This medicine is used to treat cancers of the colon and rectum, and many other cancers.
How is oxaliplatin supplied?
Day 1: ELOXATIN 85 mg/m2 intravenous infusion in 250-500 mL 5% Dextrose injection, USP and leucovorin 200 mg/m2 intravenous infusion in 5% Dextrose Injection, USP both given over 120 minutes at the same time in separate bags using a Y-line, followed by 5-fluorouracil 400 mg/m2 intravenous bolus given over 2-4 minutes.
How bad is oxaliplatin?
Oxaliplatin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
Is oxaliplatin a strong chemo drug?
Oxaliplatin is considered the most neurotoxic chemotherapy, and at the origin of peripheral neuropathies.
Is oxaliplatin a strong chemo?
How long does oxaliplatin stay in your system?
The chemotherapy itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience. Not all patients will experience all side effects but many will experience at least a few.
Do you lose hair with oxaliplatin?
Your hair may get thinner. But you are unlikely to lose all the hair from your head. Hair loss usually starts after your first or second treatment. It is almost always temporary, and your hair will usually grow back after treatment finishes.
How successful is oxaliplatin?
The probability of disease-free survival at 4 years was 69.7% and 61.0% for oxaliplatin (in combination with 5-FU/LV) and 5-FU/LV alone, respectively.
Will I lose my hair on oxaliplatin?