What does Fumarase deficiency do?

Fumarase deficiency is an inherited condition that affects the brain and other parts of the nervous system. Signs and symptoms may include a small head ( microcephaly ), severe developmental delay , poor feeding, weak muscle tone ( hypotonia ), failure to thrive, seizures , and distinctive facial features.

How do polygamous families support themselves?

Polygamists have multiple wives and dozens of children, but the state only recognizes one marriage. That leaves the rest of the wives to claim themselves as single moms with armies of children to support. Doing that means they can apply for welfare, which they do. And it’s all legal.

What is fumarate hydratase deficiency?

Clinical characteristics: Fumarate hydratase (FH) deficiency results in severe neonatal and early infantile encephalopathy that is characterized by poor feeding, failure to thrive, hypotonia, lethargy, and seizures. Dysmorphic facial features include frontal bossing, depressed nasal bridge, and widely spaced eyes.

Why did the Mormon Church stop polygamy?

The U.S. Congress renewed its attack on polygamy by disincorporating the church and seizing its assets. In 1890, church president Wilford Woodruff, fearful that the continuation of the practice of plural marriage would lead to the destruction of all Mormon temples, announced an end to official support for polygamy.

What enzyme is affected by Fumarase deficiency?

Fumarase deficiency (or fumaric aciduria) is an exceedingly rare autosomal recessive metabolic disorder in Krebs cycle characterized by a deficiency of the enzyme fumarate hydratase, which causes a buildup of fumaric acid in the urine, and a deficiency of malate.

What polygamist has the most wives?

Pre-succession crisis

Name:	Joseph Smith
Date entered polygamy:	April 5, 1841
Eventual No. of wives:	55
Notes:	Succeeded Smith as leader of the LDS Church. Was also Governor of Utah Territory from February 3, 1851 to April 12, 1858. Is probably the most famous Latter Day Saint polygamist with 55 wives.
Name:	Heber C. Kimball

Where is fumarase found?

mitochondria
Fumarase is found in mitochondria where it participates in the tricarboxylic acid (TCA) cycle. In addition to the mitochondrial fumarase, the enzyme can also be found in the cytosolic compartment.

Which Mormon has the most wives?

Presidents of the Church

Name:	Heber J. Grant
Date entered polygamy:	April 5, 1841
Eventual No. of wives:	55
Notes:	Succeeded Smith as leader of the LDS Church. Was also Governor of Utah Territory from February 3, 1851 to April 12, 1858. Is probably the most famous Latter Day Saint polygamist with 55 wives.