What is the most common HCV genotype?
HCV subtypes 1a and 1b are the most common genotypes in the United States (Fig. 3) (145). These subtypes also are predominant in Europe (35, 82, 91).
Can HCV genotype change?
Six major genotypes of the hepatitis C virus (HCV) have been described; it is assumed to be uncommon for genotypes to change in chronically infected individuals.
What are the genotypes of HCV?
The major HCV genotype worldwide is genotype 1, which accounts for 40%-80% of all isolates. Genotype 1 also may be associated with more severe liver disease and a higher risk of hepatocellular carcinoma. Genotypes 1a and 1b are prevalent in the United States, whereas in other countries, genotype 1a is less frequent.
What are the types of HCV?
Each type can be subdivided into subtypes (identified by letters) with identities of between 70 and 80%. Complete genome sequences are now available for all six HCV types and for several different subtypes of type 1 (a, b, and c), 2 (a, b, and c) and 3 (a, b, and “10a”).
What is the life expectancy of someone with hep C?
Doctor’s Response People with hepatitis C can live many years after diagnosis, but the range varies. A 2014 study showed that patients infected with hepatitis C virus died on average 15 years sooner than people who did not have the illness. With hepatitis C, the liver becomes seriously damaged due to inflammation.
What is the normal range for HCV?
Normal range for this assay is “Not Detected”. The quantitative range of this assay is 10 – 100,000,000 IU/mL (1.0 – 8.0 log IU/mL).
What are the six genotypes?
A description of the pair of alleles in our DNA is called the genotype. Since there are three different alleles, there are a total of six different genotypes at the human ABO genetic locus. The different possible genotypes are AA, AO, BB, BO, AB, and OO.
What is HCV genotype test?
A genotype is a way to put the hepatitis C virus (HCV) into categories based on similar genes. It’s important to know and understand HCV genotypes because different genotypes respond differently to medicines that treat and cure HCV. HCV has six genotypes, labeled 1 through 6.
Can HCV be cured?
A new infection with HCV does not always require treatment, as the immune response in some people will clear the infection. However, when HCV infection becomes chronic, treatment is necessary. The goal of hepatitis C treatment is to cure the disease.
