Can you be allergic to Disodium EDTA?
Get emergency medical help if you have any of these signs of an allergic reaction while taking edetate disodium (edta): hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have any of these serious side effects: feeling like you might pass out; or.
What are the side effects of disodium EDTA?
EDTA can cause abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever. It is UNSAFE to use more than 3 grams of EDTA per day, or to take it longer than 5 to 7 days. Too much can cause kidney damage, dangerously low calcium levels, and death.
Is disodium EDTA toxic?
Calcium disodium EDTA is found in food, cosmetic and industrial products and used to treat metal toxicity. The ADI is 1.1 mg per pound (2.5 mg per kg) of body weight per day — much higher than what is typically consumed. At these levels, it’s considered safe without serious side effects.
Is disodium EDTA an endocrine disruptor?
Disodium EDTA – A chelating agent, penetration enhancer and viscosity controlling agent. Studies (again, done on animals) show broad systemic effects, brain and nervous system effects at low doses, and endocrine disruption and reproductive effects at high doses.
Is EDTA an allergen?
Patch-test experts should be aware of EDTA as a potential allergen in topical medicinal and cosmetic products.
Is disodium EDTA a carcinogen?
These chelating agents are cytotoxic and weakly genotoxic, but not carcinogenic. Oral exposures to EDTA produced adverse reproductive and developmental effects in animals. Clinical tests reported no absorption of an EDTA salt through the skin.
Is disodium EDTA safe in skincare?
Used as a chelating agent in cosmetic products, meaning it prevents ingredients in a formula from binding with trace elements (mainly minerals) that can be present in water. Studies have found that EDTAs, including disodium EDTA, as used in cosmetic formulations are safe.
Can EDTA be absorbed through the skin?
Clinical tests reported no absorption of an EDTA salt through the skin. Exposure to EDTA in most cosmetic formulations, therefore, would produce systemic exposure levels well below those seen to be toxic in oral dosing studies.
Is disodium EDTA carcinogen?
These ingredients function as chelating agents in cosmetic formulations. The typical concentration of use of EDTA is less than 2%, with the other salts in current use at even lower concentrations. These chelating agents are cytotoxic and weakly genotoxic, but not carcinogenic.
Is histidine good for allergies?
Although health practitioners use histidine less frequently than other amino acids, your body uses it to make histamine, which reduces your sensitivity to allergens.
What does disodium EDTA do in skincare?
EDTA (ethylenediaminetetraacetic acid) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.
What can Versene na be used for in food?
VERSENE™ NA is a Disodium EDTA salt. It’s a food-grade chelating that can be used in pharmaceutical, food, beverages, and personal care applications. Loading… Products
What happens if you take disodium edetate intravenously?
Intravenous administration of disodium edetate can cause renal insufficiency and acute tubular necrosis [ 2 ].
What kind of chelating agent is Versene na?
VERSENE™ NA Chelating Agent | Dow Inc. A food and pharmaceutical grade product which meets the requirements of the Food Chemicals Codex and U.S. Pharmacopeia XXII. It is a partially neutralized salt of EDTA, in dry form, and is suitable for direct food applications.
Is there a contact allergy to disodium salt dihydrate?
Ethylenediaminetetraacetic acid disodium salt dihydrate (E-006) Your patch testing results indicate that you have a contact allergy to Ethylenediaminetetraacetic acid disodium salt dihydrate . It is important that you familiarize yourself with this chemical and take steps to avoid coming in contact with it.
