What is zoledronic acid injection used for?
Zoledronic acid comes as a solution (liquid) to inject into a vein over at least 15 minutes. It is usually injected by a healthcare provider in a doctor’s office, hospital, or clinic. When zoledronic acid injection is used to treat high blood levels of calcium caused by cancer it is usually given as a single dose.
When do you give Zometa?
The recommended dose of Zometa in patients with multiple myeloma and metastatic bone lesions from solid tumors for patients with creatinine clearance (CrCl) greater than 60 mL/min is 4 mg infused over no less than 15 minutes every 3 to 4 weeks. The optimal duration of therapy is not known.
What are the benefits of zoledronic acid?
Zoledronic acid reduces the activity of the osteoclasts. This can help reduce pain and strengthen the bone. It also reduces the amount of calcium that is lost from the bones. This helps calcium levels in the blood return to normal.
How do you give IV zoledronic acid?
Intravenous use. Zoledronic Acid (5 mg in 100 ml ready-to-infuse solution) is administered via a vented infusion line and given slowly at a constant infusion rate. The infusion time must not be less than 15 minutes.
What is the most common side effect of zoledronic acid?
Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.
Is zoledronic acid Safe?
Zoledronic acid had an acceptable safety profile; no adverse events were considered to be drug related. Treatment with ZA improved bone health by enhancing bone mineral density and reducing bone turnover, even in high-risk patients.
How long does zoledronic acid stay in the body?
Zoledronic acid medication is a long-acting drug. As such, it stays in your body longer than 12 months (probably more than 24 months). Therefore, delaying your treatment for a number of months will not put you at a higher risk of sustaining fragility fracture nor cause significant decline in your bone mineral density.
Does zoledronic acid affect your immune system?
It still remains unclear what role zoledronic acid plays. “We know it affects the immune system and inflammation, and both of those are important in fighting infection and cardiovascular disease,” Colon-Emeric says.
Is zoledronic acid a chemo drug?
Zoledronic acid is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and other types of cancer (such as breast, lung) that have spread to the bones. Zoledronic acid belongs to a class of drugs known as bisphosphonates .
What conditions does zoledronic acid vial treat?
Zoledronic acid belongs to the family of medications known as bisphosphonates . It is used to treat hypercalcemia (high blood calcium) for people who have cancer.
What does zoledronic acid mean?
Zoledronic acid (sometimes called zoledronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures. Zoledronic Acid This medication is used to treat high blood calcium levels that may occur with cancer. Zoledronic acid is also used with cancer chemotherapy to treat bone problems that may occur with multiple myeloma and other types of cancer that have spread to the bones. and Zometa are two different brands of zoledronic acid. Reclast is used to treat osteoporosis caused…
Can zoledronic acid cause bone pain?
You should know that zoledronic acid injection may cause severe bone, muscle, or joint pain. You may begin to feel this pain within days or months after you first receive zoledronic acid injection.
