Does bupropion help bipolar depression?

Bupropion is widely used for treating bipolar disorder (BD), and especially those with depressive mood, based on its good treatment effect, safety profile, and lower risk of phase shifting.

Can Wellbutrin trigger bipolar?

The second case, a first-time diagnosed BP-II depression with negative family history of bipolar disorder, developed hypomania after bupropion therapy was instituted. In both cases, bupropion appears to have triggered the manic/hypomanic switch, and such switching has occurred even in the presence of lithium.

What is the best antidepressant for bipolar depression?

For bipolar depression, the recommended first-line treatments are fluoxetine with olanzapine, or monotherapy with another atypical antipsychotic, quetiapine. Olanzapine or lamotrigine monotherapy can also be considered, says NICE.

What can bipolar people take for depression?

Quetiapine (Seroquel, Seroquel XR) is used for the short-term treatment of bipolar depression. Another option is olanzapine (Zyprexa) with or without fluoxetine (Prozac). The atypical antipsychotic lurasidone (Latuda) can be taken alone or with lithium or valproate for treating bipolar depression.

What happens if someone with bipolar takes antidepressants?

Antidepressants can trigger mania in people with bipolar disorder. If antidepressants are used at all, they should be combined with a mood stabilizer such as lithium or valproic acid. Taking an antidepressant without a mood stabilizer is likely to trigger a manic episode. Antidepressants can increase mood cycling.

Does Wellbutrin increase motivation?

Wellbutrin enhances the brain’s natural stimulants, dopamine and norepinephrine. These help increase mental energy and motivation/interest. Wellbutrin also helps to control addictions, increase sexual functioning (especially libido and orgasm), and aids in weight reduction.


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