How do you interpret hemoglobin electrophoresis results?
High and low values
- Higher-than-normal amounts of both hemoglobin A2 and hemoglobin F may mean a mild form of thalassemia is present.
- Hemoglobin S in moderate amounts can mean that sickle cell trait is present.
- Hemoglobin C in low amounts can mean that hemoglobin C trait is present.
What is a normal hemoglobin electrophoresis?
In adults, these are normal percentages of different hemoglobin molecules: HbA: 95% to 98% (0.95 to 0.98) HbA2: 2% to 3% (0.02 to 0.03) HbE: Absent. HbF: 0.8% to 2% (0.008 to 0.02)
What is included in hemoglobin electrophoresis?
Hemoglobin electrophoresis is a blood test that measures different types of a protein called hemoglobin in your red blood cells. It’s sometimes called “hemoglobin evaluation” or “sickle cell screen.” Newborns automatically get this test because it’s the law.
When is hemoglobin electrophoresis requested?
You acquire different abnormal types of hemoglobin by inheriting gene mutations on the genes that are responsible for producing hemoglobin. Your doctor may recommend a hemoglobin electrophoresis test to determine if you have a disorder that causes the production of abnormal hemoglobin.
What is electrophoresis test used for?
The test separates proteins in the blood based on their electrical charge. The protein electrophoresis test is often used to find abnormal substances called M proteins. The presence of M proteins can be a sign of a type of cancer called myeloma, or multiple myeloma.
How is electrophoresis done?
Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules based on their size and electrical charge. An electric current is used to move molecules to be separated through a gel. Pores in the gel work like a sieve, allowing smaller molecules to move faster than larger molecules.
How can a blood test detect thalassemia?
Several laboratory tests may be used to help detect and diagnose thalassemia:
- Complete blood count (CBC). The CBC is an evaluation of the cells in the blood.
- Blood smear (also called peripheral smear and manual differential).
- Iron studies.
- Hemoglobinopathy (Hb) evaluation (hemoglobin electrophoresis).
What is electrophoresis with diagram?
Electrophoresis is an electrokinetic process which separates charged particles in a fluid using a field of electrical charge. It is most often used in life sciences to separate protein molecules or DNA and can be achieved through several different procedures depending on the type and size of the molecules.
What is electrophoresis and its uses?
What diseases is hemoglobin electrophoresis used to diagnose?
Hemoglobin electrophoresis measures hemoglobin levels and looks for abnormal types of hemoglobin. It’s most often used to help diagnose anemia, sickle cell disease , and other hemoglobin disorders. Why do I need hemoglobin electrophoresis?
What is an electrophoresis test?
Definition Hemoglobin electrophoresis (also called Hgb electrophoresis), is a test that measures the different types of hemoglobin in the blood. The method used is called electrophoresis, a process that causes movement of particles in an electric field, resulting in formation of “bands” that separate toward one end or the other in the field.
What is a protein electrophoresis test?
Protein electrophoresis is a test that measures specific proteins in the blood. The test separates proteins in the blood based on their electrical charge. The protein electrophoresis test is often used to find abnormal substances called M proteins .
What does electrophoresis, paper mean?
Electrophoresis, Paper Electrophoresis in which paper is used as the diffusion medium. This technique is confined almost entirely to separations of small molecules such as amino acids, peptides, and nucleotides, and relatively high voltages are nearly always used.
