What are the symptoms of cat cry syndrome?
The clinical symptoms of cri du chat syndrome usually include a high-pitched cat-like cry, mental retardation, delayed development, distinctive facial features, small head size (microcephaly), widely-spaced eyes (hypertelorism), low birth weight and weak muscle tone (hypotonia) in infancy.
What does a cri du chat cry sound like?
“Cri-du-chat” means “cry of the cat” in French. Infants with the syndrome produce a high-pitched cry that sounds like a cat.
How is Cri du Chat treated?
Treatment for cri du chat syndrome There is no cure for cri du chat syndrome. Treatment aims to stimulate the child and help them to reach their full potential and can include: physiotherapy to improve poor muscle tone. speech therapy.
What is cat’s cry syndrome?
Collapse Section. Cri-du-chat (cat’s cry) syndrome, also known as 5p- (5p minus) syndrome, is a chromosomal condition that results when a piece of chromosome 5 is missing . Infants with this condition often have a high-pitched cry that sounds like that of a cat.
What causes cat cry?
Cri du chat syndrome is a chromosomal disorder caused by a partial deletion (monosomy) of a varying length of the short arm (p) of chromosome 5. Chromosomes, which are present in the nucleus of human cells, carry the genetic information for each individual.
Is Cri du Chat more common in males or females?
Cri du chat syndrome affects females more often than males. The incidence ranges from 1-15,000 to 50,000 live births. Some cases of cri du chat syndrome may go undiagnosed making it difficult to determine the true frequency of this disorder in the general population.
Can people with cri du chat syndrome live a normal life?
The survival for children with cri du chat is generally good. Most syndrome related deaths occur within the first year of life. Several children have lived to be over 50 years of age. Genetic counseling is recommended for affected individuals and their families.
Other common signs of the syndrome include excessive drooling, other distinct and unusual facial features, and severe speech delay. Dislocated hips, cleft lip, and rare kidney conditions are less common symptoms of cat cry syndrome.
How common is the cat cry syndrome?
The cat cry syndrome is one of the most common human deletion syndromes with an incidence varying between 1 in 20,000 to 1 in 50,000 births. The frequency of the syndrome among profoundly retarded patients (with an IQ less than 20) is approximately 1 in 100.
Can cats Cry syndrome be prevented?
The cat cry syndrome (CRI-du-Chat syndrome), the treatment aims to remedy possible defects and sufficiently physically and psychologically to support those affected. The cat cry syndrome itself can be prevent but due to no treatment or cure.
What is Cri du chat syndrome?
Cri du chat syndrome, is a rare genetic disorder due to chromosome deletion on chromosome 5. Its name is a French term (“cat-cry” or ” call of the cat “) referring to the characteristic cat-like cry of affected children. It was first described by Jérôme Lejeune in 1963.
