What are the types of drug toxicity?

The causes of drug toxicity can be organized in several ways and include mechanism-based (on-target) toxicity, immune hypersensitivity, off-target toxicity, and bioactivation/covalent modification.

What is drug toxicity?

Toxicity refers to how poisonous or harmful a substance can be. In the context of pharmacology, drug toxicity occurs when a person has accumulated too much of a drug in his bloodstream, leading to adverse effects on the body.

What are the toxic effects of drugs?

Behaviorally, drug toxicity can be exhibited in a variety of ways, for example, decreases in locomotor activity, loss of motor coordination, cognitive impairment. Examples of physiological effects include lesions to tissue, neuronal death, and disrupted hormonal cycles.

What is drug toxicity and poisoning?

A poison is any substance, including any drug, that has the capacity to harm a living organism. Poisoning generally implies that damaging physiological effects result from exposure to pharmaceuticals, illicit drugs, or chemicals.

What are the signs of drug toxicity?

If you take too much of a stimulant-like drug, such as cocaine, amphetamine, crack or ecstasy, overdose signs can include:

anxiety and paranoia.
restlessness or agitation.
hallucinations.
high temperature.
chest pain.
rapid breathing.
irregular or fast heartbeat.

What are signs of drug toxicity?

Do drugs build up in your system?

It depends on the medication and what kind of side effect has developed. The majority of prescription drugs are cleared out of your body rapidly by your kidneys and liver. Trace levels of a medicine may remain in the system while the liver and kidneys finish their filtering job.

How is drug toxicity prevented?

To avoid drug toxicity, patients should be proactive by keeping a careful record of which drugs they’re taking — including over-the-counter medications — and bringing that list to every doctor visit. They can also insist that their doctors consider drug toxicity when a new symptom arises.

How do drugs leave the body?

While drugs and their metabolites are mostly excreted by the kidneys into urine, drugs can also leave the body in other methods, such as breath and sweat, hence the noticeable smell of alcohol on someone who has been drinking very heavily.

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