What is a juvenile Xanthogranuloma?
A juvenile xanthogranuloma (zan tho grahn you LOH mah), or JXG, is a benign skin lump or bump caused by a collection of cells called histiocytes. These may be red, orange or tan at first, but over time may become more yellow in color. These bumps usually appear on the head, neck and trunk.
How is juvenile Xanthogranuloma treated?
Pharmacotherapy: Topical, subconjunctival, intralesional, and systemic corticosteroids are used for intraocular and orbital juvenile xanthogranuloma (JXG). Orbital lesions may respond to intralesional steroid injections. Iris lesions are treated with topical prednisolone or subconjunctival steroids.
What causes JXG?
JXG occurs more commonly in males than females, especially in younger patients with multiple lesions. The cause of JXG is not clearly understood but it is believed to result from an overproduction of a type of histiocyte cell used in the body’s immune system in response to nonspecific tissue injury.
Is juvenile Xanthogranuloma cancerous?
Juvenile xanthogranuloma, also known as JXG, is a rare, non-Langerhans cell histiocytosis that is usually benign and self-limiting.
How common is juvenile Xanthogranuloma?
Juvenile xanthogranuloma is a type of non-Langerhan’s cell histiocytosis (Class IIb). It presents as skin lesions predominantly in infants and young children, more often males, and is present at birth in 20% of cases. However, 10% of cases are adults. It is more common in Caucasians than in those of oriental origin.
How rare is JXG?
In 40–70% of patients, JXG develops in the first year of life [5]. In 5–17% of cases, the skin lesions may appear soon after birth [3, 5]. The highest incidence of JXG in adulthood is observed in patients aged 20 to 30 years, but the disease is generally rare in adults.
What is the ICD 10 code for C section?
2021 ICD-10-CM Diagnosis Code O82: Encounter for cesarean delivery without indication.
Is juvenile Xanthogranuloma genetic?
Though molecular studies have provided evidence of clonality in juvenile xanthogranuloma, in support of a neoplastic process, little is known about the genetic profile of juvenile xanthogranuloma.
Is juvenile Xanthogranuloma hereditary?
Juvenile xanthogranuloma is an uncommon proliferation of histiocytic lineage primarily affecting infants and young children, with occasional cases seen in adults.
Why do membranes rupture during pregnancy?
Rupture of the membranes near the end of pregnancy (term) may be caused by a natural weakening of the membranes or from the force of contractions. Before term, PPROM is often due to an infection in the uterus.
