What is lichenoid interface dermatitis?

What is lichenoid interface dermatitis?

The terms ‘lichenoid’ and ‘interface’ dermatitis are often used interchangeably to describe an inflammatory pattern characterized histologically by damage to the basal keratinocytes in the epidermis. The mechanism of cell damage of such cells is now best understood as apoptosis, or programmed cell death.

What causes lichenoid interface dermatitis?

This pattern is induced by ultraviolet (UV) radiation possibly mediated by tumor necrosis factor alpha (TNF-alpha). The histogenesis of lichenoid interface dermatoses is diverse, and includes both cell-mediated and humoral immune responses.

What does interface dermatitis mean?

Abstract. Interface dermatitis includes diseases in which the primary pathology involves the dermo-epidermal junction. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells.

How do you treat interface dermatitis?

Treatment

1. Corticosteroid cream.
2. Oral steroids.
3. Antihistamine creams, if an allergic response is suspected or confirmed.
4. Oral antihistamines, if an allergic response is suspected or confirmed.

Is dermatitis a lupus interface?

The 2 main connective tissue disease syndromes characterized by a cell-poor vacuolar interface dermatitis are systemic lupus erythematosus17 and dermatomyositis. 19 Dermatologists apply the designation “acute” lupus erythematosus to the macular erythematous lesions of sudden onset in patients with SLE.

How do you treat lichenoid dermatitis?

Treatments generally will include:

1. Discontinuation of medication if a drug is the culprit.
2. Steroid creams such as cortisone creams.
3. Antibiotics may also be used to help clear your skin of the rash.
4. Laser therapy for cases where skin discoloration has occurred.

How do you stop dermatitis?

These self-care habits can help you manage dermatitis and feel better:

1. Moisturize your skin.
2. Use anti-inflammation and anti-itch products.
3. Apply a cool wet cloth.
4. Take a comfortably warm bath.
5. Use medicated shampoos.
6. Take a dilute bleach bath.
7. Avoid rubbing and scratching.
8. Choose mild laundry detergent.

Is dermatitis a fungal infection?

Examples of fungal skin infections include diaper rash, systemic candidiasis, candidal paronychia, and body rash. Eczema (also called eczematous dermatitis) is a common skin condition that causes skin irritation and inflammation. red rash.

What is lupus dermatitis?

Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved by rash, the condition is called lupus dermatitis or cutaneous lupus erythematosus.

What is vacuolar interface dermatitis?

Vacuolar interface dermatitis (VAC, also known as liquefaction degeneration, vacuolar alteration or hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermal junction, with lymphocytic inflammation at the epidermis and dermis.

What does Lichenoid dermatitis look like?

Lichenoid keratosis typically looks like a small rounded or oval area on the surface of the skin. It can range in size from 3 millimeters to a centimeter or more. It may look like a sore or wart-like growth. It may appear to be inflamed or red, or like a scaly, dry patch on the skin.

Where does the term interface dermatitis come from?

The term “interface dermatitis” is therefore apt because these findings occur at the interface between the epidermis and dermis. This common thread binds otherwise disparate entities together. Other terms applied to this group of disorders include vacuolar dermatitis, vacuolar interface dermatitis, and lichenoid tissue reaction.

How is a NSData created in a program?

Creates an NSData by loading the contents of the specified file into memory. Creates an NSData by loading the contents of the specified file into memory. Creates an NSData by loading the contents of the provided stream.

Is there a limit to the size of NSData?

Data objects let simple allocated buffers (that is, data with no embedded pointers) take on the behavior of Foundation objects. The size of the data is subject to a theoretical limit of about 8 exabytes (1 EB = 10¹⁸ bytes; in practice, the limit should not be a factor). NSData is toll-free bridged with its Core Foundation counterpart, CFData.

What does handle do in NSData base class?

Handle used to represent the methods in the base class for this NSObject. Registers an object for being observed externally (using NSString keyPath). Observed changes are dispatched to the observer’s object ObserveValue (NSString, NSObject, NSDictionary, IntPtr) method.

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