What is the 189 819 Letter Word?
1. methionylthreonylthreonylglutaminylalanyl… isoleucine. You’ll notice there’s an ellipsis here, and that’s because this word, in total, is 189,819 letters long, and it’s the chemical name for the largest known protein, titin.
What does titin do in muscles?
Titin is a huge, 4.2 MDa, filamentous protein located in the sarcomere of striated muscle. Extending from its N-terminus anchored in the Z-disc to its C-terminus bound to thick filaments in the M-band, titin is largely responsible for the passive stiffness of the myocardium exhibited during diastolic filling.
What does the protein titin look like?
Titin, a polypeptide chain protein that is greater than 1µm in length and 3-4 nm in width. The protein molecule has a molecular weight of up to approximately 4 Mda. Titin is a multi-domain structure that which is found to be composed of two types of domains similar to immunoglobulin (Ig) and fibronectin.
What is the role of titin in active muscle?
Based on its structure and function in passive muscle, titin is a likely candidate to function as a dynamic spring in active muscle. For titin to play a significant role in unraveling the lingering questions of muscle mechanics and energetics, it would have to function as a dynamic spring. That is, it should engage mechanically upon activation.
How to pronounce titin in a different accent?
Record the pronunciation of this word in your own voice and play it to listen to how you have pronounced it. or pronounce in different accent or variation ? Name of a popular cartoon character.
Where is the titin protein located in the body?
The titin protein is located between the myosin thick filament and the Z disk. Titin consists primarily of a linear array of two types of modules, also referred to as protein domains (244 copies in total): type I fibronectin type III domain (132 copies) and type II immunoglobulin domain (112 copies).
Which is part of the TTN gene is titin?
Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN gene.Titin is a giant protein, greater than 1 µm in length, that functions as a molecular spring which is responsible for the passive elasticity of muscle. A variant name of a large protein
