Why are thiazides used in hypertension?
Thiazide diuretics are a common treatment for high blood pressure (hypertension). They are also used to clear fluid from the body in conditions where your body accumulates too much fluid, such as heart failure. (However, a type of diuretic called a loop diuretic is more commonly used to treat heart failure.)
Do thiazides treat hypertension?
Thiazide diuretics are a class of drugs commonly recommended as first-line treatment for raised blood pressure because they significantly reduce death, stroke and heart attacks.
How does thiazide affect blood pressure?
By decreasing sodium reabsorption, thiazide use acutely results in an increase in fluid loss to urine, which leads to decreased extracellular fluid (ECF) and plasma volume. This volume loss results in diminished venous return, increased renin release, reduced cardiac output and decreased blood pressure [7].
Which thiazide is best for hypertension?
Available data suggest HCTZ is at best equal to and very likely inferior to chlorthalidone for improving BP and clinical outcomes. Consider chlorthalidone when initiating thiazide diuretics for hypertension.
Which diuretic is best for high blood pressure?
Thiazide diuretics are recommended as one of the first drug treatments for high blood pressure. If diuretics aren’t enough to lower your blood pressure, your doctor might add other blood pressure medications to your treatment plan.
How much do thiazides lower BP?
Although in essential hypertension thiazides reduce systolic pressure by 8 to 10 mm Hg, in FHHt, thiazides reduce systolic pressure by as much as 40 mm Hg (see Figure 1).
What is the best diuretic for high blood pressure?
The main diuretic used today is hydrochlorothiazide, or HCTZ, which has fewer side effects than chlorthalidone, the diuretic used in this study. HCTZ is often combined with other diuretics into one pill.
What is the first-line treatment for hypertension?
The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.
What is the best diuretic for blood pressure?
Watermelon: Watermelon, believed to be a shielding agent against high blood pressure, expands blood vessels, thus lowering blood pressure. Parsley: Parsley, one among the best natural diuretics for high blood pressure, is enriched with potassium.
What is the most potent diuretic?
Loop diuretics are the most potent diuretics as they increase the elimination of sodium and chloride by primarily preventing reabsorption of sodium and chloride. The high efficacy of loop diuretics is due to the unique site of action involving the loop of Henle (a portion of the renal tubule)…
What are some good alternatives to furosemide?
Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure.
Why might my doctor prescribe hydrochlorothiazide?
Advertisement. Your doctor is most likely to prescribe hydrochlorothiazide, or HCTZ (Aquazide H, Diaqua, Hydrocot and others) to treat fluid retention. This can happen in people with conditions such as high blood pressure or kidney and heart problems, and those having steroid or hormone therapy.
