Should I be worried if my B12 is high?
There is no upper limit for vitamin B-12 intake because consuming high levels does not cause problems. However, having naturally high levels of vitamin B-12 in the body may be a cause for concern, as it suggests a severe underlying condition.
Is B12 level of 1500 too high?
There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.
Is B12 level of 1200 too high?
The normal range for vitamin B12 (total) is between 200 – 1100 ng/L (nanograms per liter), 200 – 1100 pg/mL (picograms per milliliter), or 148 – 811 pmol/L (picomoles per liter). The normal range for active vitamin B12 (holoTC) is around 20 – 134 pmol/L (picomoles per liter).
How do I lower my vitamin B12?
In many older adults, the secretion of hydrochloric acid in the stomach is reduced, causing a reduction in the absorption of vitamin B12. If your body has difficulty absorbing vitamin B12, your doctor may recommend intramuscular injections of B12 to increase your levels.
What is the treatment for high vitamin B12?
You can change your diet to include vitamin B12-fortified grains, a supplement or B12 injections, or a high-dose oral vitamin B12 if you are deficient. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12.
Is High B12 serious?
Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.
What are the symptoms of high B12 levels?
High doses of vitamin B-12, such as those used to treat a deficiency, might cause:
- Headache.
- Nausea and vomiting.
- Diarrhea.
- Fatigue or weakness.
- Tingling sensation in hands and feet.
What does a high vitamin B12 level indicate?
High levels of vitamin B-12 can be a sign of liver disease, certain types of leukemia, or diabetes. Vitamin B-12 deficiency is a common condition. Between 1.5 and 15 percent of Americans have low levels of vitamin B-12, according to the National Institutes of Health .
Why do I have high B12 levels?
Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)
What foods have high vitamin B12?
Vitamin B12 is naturally present in foods of animal origin, including fish, meat, poultry, eggs, and dairy products [5]. In addition, fortified breakfast cereals and fortified nutritional yeasts are readily available sources of vitamin B12 that have high bioavailability [12,13].
What happens if vitamin B12 is high?
However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.
What causes elevated vitamin B12 levels in blood?
The most obvious cause of an elevated vitamin B12 level is taking too much of the vitamin in the form of supplements. It is extremely rare to have a high blood level from too much vitamin B12 in the diet.
What are the symptoms of a high vitamin B12?
High vitamin B12 is a symptom of an underlying illness that causes the amount in your blood to increase. For example, a damaged liver may release the vitamin out of storage and into the blood. In early stages, illnesses associated with high vitamin B12 often have generic symptoms, such as fatigue and loss of appetite.
If you have elevated vitamin B12 levels in your bloodstream, it is a sign of a serious illness. The most common diseases associated with high levels of the vitamin are kidney failure, blood cancers, leukemia, liver disease, polycythemia vera, and hypereosinophilic syndrome.
What does high B12 blood levels really mean?
High blood B12 levels can occur in liver conditions such as cirrhosis and hepatitis. Alcoholic liver disease is an example of a liver condition associated with high vitamin B12 . With alcoholic liver disease, vitamin B12 as well as its carrier proteins can be elevated.
