What is a normal rubella titer?
Reference Range: 7 IU/mL or less: Negative – No significant level of detectable rubella IgG antibody. 8-9 IU/mL: Equivocal – Repeat testing in 10-14 days may be helpful. 10 IU/mL or greater: Positive – IgG antibody to rubella detected, which may indicate a current or previous exposure/immunization to rubella.
What is the normal range of rubella IgG in pregnancy?
Results: Quantitative analysis of the IgG levels showed noticeable variability that ranged between 24-143 IU/ml (average 94). One hundred and forty-five (91%) out of 160 women had rubella IgG levels of above 50 IU/ml with a range of 54-143 IU/ml (average 92) while 15 (9%) had a level between 24-46 IU/ml (average 38).
How do you read a rubella titer result?
Here’s how your IgG test results stack up:
- A positive test is 1.0 or higher. That means you have rubella antibodies in your blood and are immune to future infection.
- A negative test is 0.7 or lower. You have too few antibodies to make you immune. If you have any, they can’t be detected.
What is the normal range of rubella IgM?
|19.9 AU/mL or less:||Not Detected.|
|20.0 – 24.9 AU/mL:||Indeterminate – Repeat testing in 10-14 days may be helpful.|
|25.0 AU/mL or greater:||Detected – IgM antibody to rubella detected, which may indicate a current or recent infection or immunization.|
How long does a rubella titer take?
To confirm the IgM result, the health practitioner may order an IgG test to establish a baseline level of antibody and may repeat the IgG test again (tested together with the first specimen) in 7-21 days to look for a significant increase in the amount (titer) present, indicating a recent rubella infection.
What does high titer mean?
In certain conditions, a low titer may essentially indicate the efficient removal of infectious pathogens by the immune system. In contrast, a high titer may simply be due to the presence of residual antibodies from a previous infection, or unsuccessful attempts to form antigen-antibody complexes.
What happens if rubella IgG is high?
A positive rubella IgG test result is good—it means that you are immune to rubella and cannot get the infection. This is the most common rubella test done.
How does rubella affect pregnancy?
Pregnant women who contract rubella are at risk for miscarriage or stillbirth, and their developing babies are at risk for severe birth defects with devastating, lifelong consequences. CRS can affect almost everything in the developing baby’s body. The most common birth defects from CRS can include: Deafness.
What is a high titer level?
What happens if rubella is high?
Women who are infected with rubella may feel arthritis in their fingers, wrists and knees. This complication is rare in men or children who get rubella. In rare cases, rubella can cause serious problems, including brain infections and bleeding problems.
What does it mean when rubella IgG is positive?
A positive rubella IgG test result is good—it means that you are immune to rubella and cannot get the infection. This is the most common rubella test done. Negative: Less than 7 IU/mL IgG antibodies and less than 0.9 IgM antibodies.
What do you do if rubella IgM is positive?
The presence of IgM rubella antibodies in the blood indicates a recent infection while the presence of IgG antibodies may indicate a recent or past rubella infection, or indicate that a rubella vaccine (a measles, mumps, rubella vaccine) has been given and is providing adequate protection.