Which of the following endocrinopathies can cause diabetes mellitus?
Endocrinopathies. Several hormones (e.g., growth hormone, cortisol, glucagon, epinephrine) antagonize insulin action. Excess amounts of these hormones (e.g., acromegaly, Cushing’s syndrome, glucagonoma, pheochromocytoma, respectively) can cause diabetes.
How does acromegaly cause diabetes?
Insulin resistance, hyperinsulinaemia and increased gluconeogenesis combine to produce a metabolic milieu which leads to the development of diabetes in acromegaly. Treatment of acromegaly should ameliorate abnormalities of glucose metabolism, due to reversal of insulin resistance and a reduction in gluconeogenesis.
When should I see a endocrinologist?
An endocrinologist is a medical specialist who treats people with a range of conditions that are caused by problems with hormones, such as diabetes, menopause and thyroid problems. Hormones are part of the endocrine system, series of glands that produce and secrete hormones that control many different bodily functions.
What is the meaning of Endocrinopathy?
Endocrinopathy: A disease of an endocrine gland. The term endocrinopathy is commonly used as a medical term for a hormone problem. Common endocrinopathies include hyperthyroidism and hypothyroidism.
Is diabetes a metabolic or endocrine disorder?
Diabetes mellitus is the most common endocrine/metabolic disorder. It affects 6.5% of the U.S. population.
What is the diagnostic criteria for metabolic syndrome?
You are diagnosed with metabolic syndrome if you have three or more of the following: A waistline of 40 inches or more for men and 35 inches or more for women (measured across the belly) A blood pressure of 130/85 mm Hg or higher or are taking blood pressure medications. A triglyceride level above 150 mg/dl.
Can acromegaly cause type 2 diabetes?
Acromegaly is an uncommon secondary cause of diabetes. Excess GH: 1) stimulates gluconeogenesis and lipolysis, causing hyperglycemia and elevated free fatty acid levels; 2) leads to both hepatic and peripheral insulin resistance, with compensatory hyperinsulinemia.
What percentage of patients diagnosed with acromegaly have diabetes?
DM was diagnosed in 51 patients with acromegaly (52.5%) and 14.3% of the general population (P<0.001). The prevalence of ECMDs was also higher in patients with acromegaly than in the general population and in the high-risk group; only 22% of patients with acromegaly were normoglycaemic.
What will an endocrinologist do on a first visit?
When you first visit, the endocrinologist will ask you a series of questions to learn more about your symptoms, health habits, other medical conditions, medications, and family history of hormone-related problems. They will consult with your referring doctor and review your medical records.
What hormones do opioids affect?
In humans and laboratory animals, opioids generally increase GH and prolactin and decrease LH, testosterone, estradiol, and oxytocin. In humans, opioids increase TSH, whereas in rodents, TSH is decreased.
